Schedule

 8.00-9.00      Registration

9.00-9.10      Opening of the symposium         Leena Peltonen, Helsinki

9.10-9.50      Keynote lecture                  
                        George Eisenbarth, University of Colorado, USA
                    Autoimmune diseases in the postgenome era

                        Role of AIRE in central and peripheral tolerance
9.50-10.30     Mark Anderson, University of California, San Francisco, USA
                   AIRE as an immunological regulator

10.30-11.00   Coffee break & Poster session

11.00-11.40   Bruno Kyewski, German Cancer Research Center, Heidelberg, Germany
                   Mechanisms of AIRE-directed gene regulation

11.40 -12.20  Christopher Goodnow, The Australian National University, Australia
                   AIRE and autoimmune pathogenesis

12.20-13.30   Lunch

         Genome-wide profiles of autoimmunity
13.30 -14.10  Leena Peltonen, National Public Health Institute, Helsinki and Sanger Institute, Oxford,             UK
                   Use of special populations to characterize the molecular background of autoimmunity

14.10-14.50   Stephen Sawcer, University of Cambridge, UK
                   Genes behind multiple sclerosis

14.50-15.30  Kathryn Wood, University of Oxford, UK
                 Tolerance in Transplantation

15.30-16.30   Coffee break & Poster session

T cells in autoimmunity

16.30-17.10   Georg Holländer, University of Basel, Switzerland
                   Thymus organogenesis and T cell development

17.10-17.50   Simon Sakaguchi, Kyoto University, Japan
                   Role of regulatory T cells in tolerance and autoimmunity

19.30            Symposium dinner